Coadministration of the FNIII14 Peptide Synergistically Augments the Anti-Cancer Activity of Chemotherapeutic Drugs by Activating Pro-Apoptotic Bim.

Coadministration of the FNIII14 Peptide Synergistically Augments the Anti-Cancer Activity of Chemotherapeutic Drugs by Activating Pro-Apoptotic Bim.

The acquisition of drug resistance mediated by the interaction of tumor cells with the extracellular matrix (ECM), commonly referred to as cell adhesion-mediated drug resistance (CAM-DR), has been observed not only in hematopoietic tumor cells but also in solid tumor cells. We have previously demons...

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Main Authors: Takuya Iyoda, Yumi Nagamine, Yoshitomi Nakane, Yuya Tokita, Shougo Akari, Kazuki Otsuka, Motomichi Fujita, Keisuke Itagaki, You-Ichi Takizawa, Hiroaki Orita, Toshiyuki Owaki, Jyunichi Taira, Ryo Hayashi, Hiroaki Kodama, Fumio Fukai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5021278?pdf=render

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http://europepmc.org/articles/PMC5021278?pdf=render

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