Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma

Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma

Abstract Background Over the past decade, newly designed cancer therapies have not significantly improved the survival of patients diagnosed with Malignant Pleural Mesothelioma (MPM). Among a limited number of genes that are frequently mutated in MPM several of them encode proteins that belong to th...

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Bibliographic Details
Main Authors: Claudio Pulito, Etleva Korita, Andrea Sacconi, Mariacristina Valerio, Luca Casadei, Federica Lo Sardo, Federica Mori, Maria Ferraiuolo, Giuseppe Grasso, Anna Maidecchi, Jacopo Lucci, Marius Sudol, Paola Muti, Giovanni Blandino, Sabrina Strano
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
HIPPO tumour suppressor pathway
YAP
Mesothelioma
Phytonutrient
Cancer metabolism
Online Access:http://link.springer.com/article/10.1186/s13046-019-1352-3

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http://link.springer.com/article/10.1186/s13046-019-1352-3

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