The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa.
Understanding how beneficial mutations affect fitness is crucial to our understanding of adaptation by natural selection. Here, using adaptation to the antibiotic rifampicin in the opportunistic pathogen Pseudomonas aeruginosa as a model system, we investigate the underlying distribution of fitness...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2646133?pdf=render |