The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2.

Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape. In publishe...

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Bibliographic Details
Main Authors: Marilina de Sautu, Tobias Herrmann, Gustavo Scanavachi, Simon Jenni, Stephen C Harrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011750&type=printable