CLIC2α Chloride Channel Orchestrates Immunomodulation of Hemocyte Phagocytosis and Bactericidal Activity in Crassostrea gigas

CLIC2α Chloride Channel Orchestrates Immunomodulation of Hemocyte Phagocytosis and Bactericidal Activity in Crassostrea gigas

Summary: Chloride ion plays critical roles in modulating immunological interactions. Herein, we demonstrated that the anion channel CLIC2α mediates Cl− flux to regulate hemocytes functions in the Pacific oyster (Crassostrea gigas). Specifically, during infection by Vibrio parahemolyticus, chloride i...

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Bibliographic Details
Main Authors: Xiangyu Zhang, Fan Mao, Nai-Kei Wong, Yongbo Bao, Yue Lin, Kunna Liu, Jun Li, Zhiming Xiang, Haitao Ma, Shu Xiao, Yang Zhang, Ziniu Yu
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Cell Biology
Immunology
Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305150

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http://www.sciencedirect.com/science/article/pii/S2589004220305150

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