Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration

Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration

Abstract Age-related macular degeneration (AMD) is a major vision-threatening disease. Although mesenchymal stem cells (MSCs) exhibit beneficial neural protective effects, their limited differentiation capacity in vivo attenuates their therapeutic function. Therefore, the differentiation of MSCs int...

Full description

Bibliographic Details
Main Authors: Xiaoman Zhu, Zhiyang Chen, Li Wang, Qingjian Ou, Zhong Feng, Honglei Xiao, Qi Shen, Yingao Li, Caixia Jin, Jing-Ying Xu, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Zhiguo Xu, Guo-Tong Xu, Lixia Lu, Haibin Tian
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05199-5

Internet

https://doi.org/10.1038/s41419-022-05199-5

Similar Items