Cerium-Doped Self-Assembling Nanoparticles as a Novel Anti-Oxidant Delivery System Preserving Mitochondrial Function in Cortical Neurons Exposed to Ischemia-like Conditions

Cerium-Doped Self-Assembling Nanoparticles as a Novel Anti-Oxidant Delivery System Preserving Mitochondrial Function in Cortical Neurons Exposed to Ischemia-like Conditions

Neurodegenerative diseases are characterized by mitochondrial dysfunction leading to abnormal levels of reactive oxygen species (ROS), making the use of ROS-scavenging nanomaterials a promising therapeutic approach. Here, we combined the unique ROS-scavenging properties of cerium-based nanomaterials...

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Bibliographic Details
Main Authors: Valeria Nele, Valentina Tedeschi, Virginia Campani, Raffaella Ciancio, Alessia Angelillo, Sossio Fabio Graziano, Giuseppe De Rosa, Agnese Secondo
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
lipid nanoparticles
ROS-scavenging
mitochondrial disfunction
cerium oxide
neurons
hypoxia
Online Access:https://www.mdpi.com/2076-3921/12/2/358

Internet

https://www.mdpi.com/2076-3921/12/2/358

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