MALDI Imaging, a Powerful Multiplex Approach to Decipher Intratumoral Heterogeneity: Combined Hepato-Cholangiocarcinomas as Proof of Concept

MALDI Imaging, a Powerful Multiplex Approach to Decipher Intratumoral Heterogeneity: Combined Hepato-Cholangiocarcinomas as Proof of Concept

Combined hepato-cholangiocarcinomas (cHCC-CCA) belong to the spectrum of primary liver carcinomas, which include hepatocellular carcinomas (HCC) and intrahepatic cholangiocarcinomas (iCCA) at both ends of the spectrum. Mainly due to the high intratumor heterogeneity of cHCC-CCA, its diagnosis and pa...

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Bibliographic Details
Main Authors: Elia Gigante, Hélène Cazier, Miguel Albuquerque, Samira Laouirem, Aurélie Beaufrère, Valérie Paradis
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
combined hepato-cholangiocarcinomas
diagnosis
intratumoral heterogeneity
MALDI imaging
immunohistochemistry
in silico digestion
Online Access:https://www.mdpi.com/2072-6694/15/7/2143

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https://www.mdpi.com/2072-6694/15/7/2143

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