Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy

Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy

Malignant melanoma is a life-threatening form of skin cancer with a low response rate to single-agent chemotherapy. Although combined therapies of metformin (MET) and doxorubicin (DOX) are effective in treating a variety of cancers, including breast cancer, their different physicochemical properties...

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Bibliographic Details
Main Authors: Mingming Song, Wentao Xia, Zixuan Tao, Bin Zhu, Wenxiang Zhang, Chang Liu, Siyu Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
drug delivery
melanoma
combination therapy
nanoparticles
metformin
doxorubicin
panoptosis
Online Access:http://dx.doi.org/10.1080/10717544.2021.1898703

Internet

http://dx.doi.org/10.1080/10717544.2021.1898703

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