Modular Approaches to Synthesize Activity- and Affinity-Based Chemical Probes

Combinatorial and modular methods to synthesize small molecule modulators of protein activity have proven to be powerful tools in the development of new drug-like molecules. Over the past decade, these methodologies have been adapted toward utilization in the development of activity- and affinity-ba...

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Bibliographic Details
Main Authors: Antonie J. van der Zouwen, Martin D. Witte
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.644811/full