Inference on spatial heterogeneity in tumor microenvironment using spatial transcriptomics data

Abstract In the tumor microenvironment (TME), functional interactions among tumor, immune, and stromal cells and the extracellular matrix play key roles in tumor progression, invasion, immune modulation, and response to treatment. Intra‐tumor heterogeneity is ubiquitous not only at the genetic and t...

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Bibliographic Details
Main Authors: Antara Biswas, Bassel Ghaddar, Gregory Riedlinger, Subhajyoti De
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Computational and Systems Oncology
Subjects:
Online Access:https://doi.org/10.1002/cso2.1043