Inference on spatial heterogeneity in tumor microenvironment using spatial transcriptomics data
Abstract In the tumor microenvironment (TME), functional interactions among tumor, immune, and stromal cells and the extracellular matrix play key roles in tumor progression, invasion, immune modulation, and response to treatment. Intra‐tumor heterogeneity is ubiquitous not only at the genetic and t...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2022-09-01
|
Series: | Computational and Systems Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/cso2.1043 |