Significant difference in Th1/Th2 paradigm induced by tuberculosis-specific antigens between IGRA-positive and IGRA-negative patients

Significant difference in Th1/Th2 paradigm induced by tuberculosis-specific antigens between IGRA-positive and IGRA-negative patients

False negative interferon-γ release assay (IGRA) results constitute the major dilemma for the diagnosis of tuberculosis (TB) infections. Herein, we conducted a cohort study to compare the host immunological response to TB-specific antigens between active TB patients with positive and negative IGRA r...

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Bibliographic Details
Main Authors: Qiang Li, Weicong Ren, Jinfeng Yuan, Haiping Guo, Yuanyuan Shang, Wei Wang, Junhua Pan, Mengqiu Gao, Yu Pang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
cytokine
interferon-γ release assays
tuberculosis
T cell
diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.904308/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.904308/full

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