Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification

Background: Patients receiving dialysis have high cardiovascular risk in part due to extensive vascular calcification. In the CaLIPSO study, infusion of hexasodium fytate (SNF472), the hexasodium salt of inositol hexaphosphate, for 52 weeks thrice weekly during hemodialysis significantly reduced pro...

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Bibliographic Details
Main Authors: Joan Perelló, Joan Alberti, Juan Vicente Torres, Miguel D. Ferrer, M. Mar Perez, Firas Bassissi, Alex Gold, Paolo Raggi, Glenn M. Chertow, Carolina Salcedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
pharmacokinetics
pharmacodynamics
hexasodium fytate
SNF472
calcification
cardiovascular
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1325186/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1325186/full

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