Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease

Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease

Histone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was histone acetyltransferase 1 (HAT1), but it remains one of the least understood acetyltransferases. HAT1 catalyzes the ac...

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Bibliographic Details
Main Authors: Miguel A. Ortega, Diego De Leon-Oliva, Cielo Garcia-Montero, Oscar Fraile-Martinez, Diego Liviu Boaru, María del Val Toledo Lobo, Ignacio García-Tuñón, Mar Royuela, Natalio García-Honduvilla, Julia Bujan, Luis G. Guijarro, Melchor Alvarez-Mon, Miguel Ángel Alvarez-Mon
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
HAT1
acetyltransferase
histones H3H4
epigenetics
noncanonical roles
cancer
Online Access:https://www.mdpi.com/2073-4425/14/4/915

Internet

https://www.mdpi.com/2073-4425/14/4/915

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