Comparison of computational methods for the identification of topologically associating domains

Comparison of computational methods for the identification of topologically associating domains

Abstract Background Chromatin folding gives rise to structural elements among which are clusters of densely interacting DNA regions termed topologically associating domains (TADs). TADs have been characterized across multiple species, tissue types, and differentiation stages, sometimes in associatio...

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Bibliographic Details
Main Authors: Marie Zufferey, Daniele Tavernari, Elisa Oricchio, Giovanni Ciriello
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Genome Biology
Subjects:
Topologically associating domain
Hi-C
Method comparison
Online Access:http://link.springer.com/article/10.1186/s13059-018-1596-9

Internet

http://link.springer.com/article/10.1186/s13059-018-1596-9

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