Cardiac Protection of a Novel Lupane-Type Triterpenoid from Injuries Induced by Hypoxia–Reperfusion

Cardiac Protection of a Novel Lupane-Type Triterpenoid from Injuries Induced by Hypoxia–Reperfusion

Myocardial ischemia–reperfusion injury (MIRI) leads to cardiac remodeling and heart failure associated with acute myocardial infarction, which is one of the leading causes of death worldwide. Betulinic acid (BA), a widely distributed lupane-type triterpenoid, has been reported to possess antioxidati...

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Bibliographic Details
Main Authors: Beibei Guo, Jiaxin Cao, Yi Liu, Yuhang Wang, Yi Qian, Guangtong Chen, Weizhong Zhu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
triterpenoids
cardiac protection
oxidative stress
PI3K/Akt
Online Access:https://www.mdpi.com/1422-0067/23/16/9473

Internet

https://www.mdpi.com/1422-0067/23/16/9473

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