Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination

Abstract Gardasil® (Merck) and Cervarix® (GlaxoSmithKline) both provide protection against infection with Human Papillomavirus 16 (HPV16) and Human Papillomavirus 18 (HPV18), that account for around 70% of cervical cancers. Both vaccines have been shown to induce high levels of neutralizing antibodi...

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Bibliographic Details
Main Authors: Vicky Roy, Wonyeong Jung, Caitlyn Linde, Emily Coates, Julie Ledgerwood, Pamela Costner, Galina Yamshchikov, Hendrik Streeck, Boris Juelg, Douglas A. Lauffenburger, Galit Alter
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00628-8