Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis
The promiscuous GTPase Rab35 has been shown to be involved in many important cellular functions. In this article, Francis et al. illustrate how Rab35 acts as a critical brake to actin remodeling during sprouting angiogenesis and how it is necessary for proper blood vessel development.
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-32853-5 |