Combined transcriptomic and ChIPseq analyses of the Bordetella pertussis RisA regulon

ABSTRACTThe regulation of Bordetella pertussis virulence is mediated by the two-component system BvgA/S, which activates the transcription of virulence-activated genes (vags). In the avirulent phase, the vags are not expressed, but instead, virulence-repressed genes (vrgs) are expressed, under the c...

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Bibliographic Details
Main Authors: Loïc Coutte, Rudy Antoine, Stephanie Slupek, Camille Locht
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msystems.00951-23