Combined transcriptomic and ChIPseq analyses of the Bordetella pertussis RisA regulon
ABSTRACTThe regulation of Bordetella pertussis virulence is mediated by the two-component system BvgA/S, which activates the transcription of virulence-activated genes (vags). In the avirulent phase, the vags are not expressed, but instead, virulence-repressed genes (vrgs) are expressed, under the c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2024-04-01
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Series: | mSystems |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/msystems.00951-23 |