Renal and vascular effects of Crotalus durissus cumanensis venom and its crotoxin fraction

Renal and vascular effects of Crotalus durissus cumanensis venom and its crotoxin fraction

In this study, we evaluated the actions of Crotalus durissus cumanensis venom (CDCmV), and its crotoxin (Crtx) fraction, on renal and vascular functions in Wistar rats. In isolated perfused kidneys, CDCmV (10 µg/mL) significantly increased the perfusion pressure (PP) from 110.7 ± 2.4 to 125.3 ± 2.8...

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Bibliographic Details
Main Authors: TP Pereira, RRPP Bezerra de Menezes, AFC Torres, TS Brito, FJ Batista-Lima, JFC Vinhote, DF Sousa, RM Ximenes, MH Toyama, EBS Diz Filho, PJC Magalhães, HSA Monteiro, AMC Martins
Format: Article
Language:English
Published: SciELO 2011-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
kidney
vascular injuries
Crotalus durissus cumanensis
crotoxin
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000300014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000300014

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