The Effect of Polymorphisms in the CYP2D6 and CYP2C9 Genes on the Clinical Efficacy of Tramadol and Ketorolac When Using the Accelerated Recovery Protocol in Patients With Uncomplicated Acute Calculous Cholecystitis Who Underwent Cholecystectomy

The Effect of Polymorphisms in the CYP2D6 and CYP2C9 Genes on the Clinical Efficacy of Tramadol and Ketorolac When Using the Accelerated Recovery Protocol in Patients With Uncomplicated Acute Calculous Cholecystitis Who Underwent Cholecystectomy

Relevance. One of the key components of the accelerated recovery protocols (ARP), in addition to minimizing the surgical approach, is an adequate postoperative analgesia. Despite this, applied postoperative analgesia combinations are not devoid of drawbacks, such as lack of effective postoperative a...

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Bibliographic Details
Main Authors: A. A. Muradyan, D. A. Blagovestnov, D. A. Sychev, P. A. Yartsev, M. L. Rogal, L. N. Kerimova, V. T. Koroshvili, I. A. Yepifanova
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2020-10-01
Series:Неотложная медицинская помощь
Subjects:
tramadol
ketorolac
videolaparoscopic cholecystectomy
cyp2d6
cyp2c9
cytochrome p 450
pharmacogenetics
eras
Online Access:https://www.jnmp.ru/jour/article/view/948

Internet

https://www.jnmp.ru/jour/article/view/948

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