The Impact of HBV Quasispecies Features on Immune Status in HBsAg+/HBsAb+ Patients With HBV Genotype C Using Next-Generation Sequencing

The Impact of HBV Quasispecies Features on Immune Status in HBsAg+/HBsAb+ Patients With HBV Genotype C Using Next-Generation Sequencing

BackgroundThis study aimed to explore the molecular mechanism of the coexistence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) serological pattern via intensive characterization of HBV s gene in both chronic hepatitis B (CHB) and hepatocellular carcinoma (HCC) patie...

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Bibliographic Details
Main Authors: Ying Wang, Xiao Xiao, Shipeng Chen, Chenjun Huang, Jun Zhou, Erhei Dai, Ya Li, Lijuan Liu, Xianzhang Huang, Zhiyuan Gao, Chuanyong Wu, Meng Fang, Chunfang Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
next-generation sequencing (NGS)
hepatitis B virus (HBV)
quasispecies
hepatitis B surface antigen (HBsAg)
hepatitis B surface antibody (HBsAb)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.775461/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.775461/full

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