F/YGG-motif is an intrinsically disordered nucleic-acid binding motif

F/YGG-motif is an intrinsically disordered nucleic-acid binding motif

Heterogeneous nuclear ribonucleoproteins (hnRNP) function in RNA processing, have RNA-recognition motifs (RRMs) and intrinsically disordered, low-complexity domains (LCDs). While RRMs are drivers of RNA binding, there is only limited knowledge about the RNA interaction by the LCD of some hnRNPs. Her...

Full description

Bibliographic Details
Main Authors: Joris Van Lindt, Tamas Lazar, Donya Pakravan, Manon Demulder, Attila Meszaros, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:RNA Biology
Subjects:
liquid-liquid phase separation
disordered proteins
nucleic acid interaction
low complexity domain
sequence motif
Online Access:http://dx.doi.org/10.1080/15476286.2022.2066336

Internet

http://dx.doi.org/10.1080/15476286.2022.2066336

Similar Items