The influence of cell concentration at cryopreservation on neutrophil engraftment after autologous peripheral blood stem cell transplantation

Background: Peripheral blood stem cell concentrations are traditionally adjusted to 20–40 × 106 leukocytes/mL prior to freezing. This low cell concentration at cryopreservation implies larger volumes with more dimethyl sulfoxide being used, and higher cost and toxicity at the time of transplant. Hig...

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Bibliographic Details
Main Authors: Olga Margareth Wanderley de Oliveira Félix, Gisela Tunes, Valéria Cortez Ginani, Paulo César Simões, Daniele Porto Barros, Elizabete Delbuono, Maria Teresa de Seixas Alves, Antonio Sérgio Petrilli, Maria Lúcia de Martino Lee, Roseane Vasconcelos Gouveia, Victor Gottardello Zecchin, Adriana Seber
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137918300555