Perinatal Resveratrol Therapy to Dioxin-Exposed Dams Prevents the Programming of Hypertension in Adult Rat Offspring

Perinatal Resveratrol Therapy to Dioxin-Exposed Dams Prevents the Programming of Hypertension in Adult Rat Offspring

Exposure to environmental chemicals during pregnancy and lactation is a contributing factor in gut microbiota dysbiosis and linked to programming of hypertension. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic dioxin, induces toxic effects by mediating aryl hydrocarbon receptor (AHR). Re...

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Bibliographic Details
Main Authors: Chien-Ning Hsu, Chih-Hsing Hung, Chih-Yao Hou, Chi-I. Chang, You-Lin Tain
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
developmental origins of health and disease (DOHaD)
gut microbiota
resveratrol
aryl hydrocarbon receptor
3,3-dimethyl-1-butanol
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Online Access:https://www.mdpi.com/2076-3921/10/9/1393

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https://www.mdpi.com/2076-3921/10/9/1393

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