Intelligent guide RNA: dual toehold switches for modulating luciferase in the presence of trigger RNA

Abstract The CRISPR system finds extensive application in molecular biology, but its continuous activity can yield adverse effects. Leveraging programmable CRISPR/Cas9 function via nano-device mediation effectively mitigates these drawbacks. The integration of RNA-sensing platforms into CRISPR thus...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Mohammad Hashemabadi, Hossein Ali Sasan, Saman Hosseinkhani, Mojdeh Amandadi, Azadeh Samareh Gholami, Majid Sadeghizadeh
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2024-10-01
श्रृंखला:Communications Biology
ऑनलाइन पहुंच:https://doi.org/10.1038/s42003-024-06988-8