Intelligent guide RNA: dual toehold switches for modulating luciferase in the presence of trigger RNA
Abstract The CRISPR system finds extensive application in molecular biology, but its continuous activity can yield adverse effects. Leveraging programmable CRISPR/Cas9 function via nano-device mediation effectively mitigates these drawbacks. The integration of RNA-sensing platforms into CRISPR thus...
| Main Authors: | , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Nature Portfolio
2024-10-01
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| 叢編: | Communications Biology |
| 在線閱讀: | https://doi.org/10.1038/s42003-024-06988-8 |