Characterization of Sigma-2 Receptor—Specific Binding Sites Using [<sup>3</sup>H]DTG and [<sup>125</sup>I]RHM-4
The sigma-2 receptor/transmembrane protein 97 (σ2R/TMRM97) is a promising biomarker of tumor proliferation and a target for cancer therapy. [<sup>3</sup>H]DTG has been used to evaluate σ2R/TMEM97 binding affinity in compound development studies. However, [<sup>3</sup>H]DTG ha...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
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| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/15/12/1564 |