The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans.

The mitochondrial unfolded protein response (UPRmt) is a surveillance pathway that defends proteostasis in the "powerhouse" of the cell. Activation of the UPRmt protects against stresses imposed by reactive oxygen species, respiratory chain deficits, and pathologic bacteria. Consistent wit...

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Bibliographic Details
Main Authors: Salvador Peña, Teresa Sherman, Paul S Brookes, Keith Nehrke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4961406?pdf=render