Inhibition of Tyrosinase by Mercury Chloride: Spectroscopic and Docking Studies

Inorganic mercury compounds have been used in skin-lightening products since ancient times. Although a previous study demonstrated that mercury impeded the transfer of Cu2+ to the apotyrosinase, the effect of mercury on tyrosinase is still unclear. In the present study, the mechanism of mercury chlo...

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Bibliographic Details
Main Authors: Jianmin Chen, Yaling Ye, Mengnan Ran, Qinglian Li, Zhipeng Ruan, Nan Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00081/full