Chondroitinase ABC Administration Facilitates Serotonergic Innervation of Motoneurons in Rats With Complete Spinal Cord Transection

Chondroitinase ABC Administration Facilitates Serotonergic Innervation of Motoneurons in Rats With Complete Spinal Cord Transection

Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Previous studies demonstrated that the administration of ChABC after spinal cord injury promotes nerve regeneration by re...

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Bibliographic Details
Main Authors: Masahito Takiguchi, Kanae Miyashita, Kohei Yamazaki, Kengo Funakoshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Integrative Neuroscience
Subjects:
complete transection
perineuronal net
chondroitin sulfate proteoglycan
spinal cord injury
serotonin
Online Access:https://www.frontiersin.org/articles/10.3389/fnint.2022.881632/full

Internet

https://www.frontiersin.org/articles/10.3389/fnint.2022.881632/full

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