The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice

The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice

<p>Abstract</p> <p>Background</p> <p>Intestinal inflammation is partly driven by enteroglial-derived S100B protein. The antiprotozoal drug pentamidine directly blocks S100B activity. We aimed to investigate the effect of pentamidine on intestinal inflammation using an a...

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Bibliographic Details
Main Authors: Esposito Giuseppe, Capoccia Elena, Sarnelli Giovanni, Scuderi Caterina, Cirillo Carla, Cuomo Rosario, Steardo Luca
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Neuroinflammation
Subjects:
Pentamidine
Acute colitis
S100B protein
Enteric glia
Online Access:http://www.jneuroinflammation.com/content/9/1/277

Internet

http://www.jneuroinflammation.com/content/9/1/277

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