Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway

Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway

Abstract Background Tobacco smoke (TS) critically contributes to the development of hepatocellular carcinoma. Cancer stem cells (CSCs) induced by TS is an early event in the initiation of carcinogenesis. Tumor specific microenvironment including inflammatory factors is key mediator for maintaining t...

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Bibliographic Details
Main Authors: Chunfeng Xie, Jianyun Zhu, Xueqi Wang, Jiaqi Chen, Shanshan Geng, Jieshu Wu, Caiyun Zhong, Xiaoting Li
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Tobacco smoke
Liver CSCs
IL-33
p38 MAPK
EMT
Online Access:http://link.springer.com/article/10.1186/s13046-019-1052-z

Internet

http://link.springer.com/article/10.1186/s13046-019-1052-z

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