Expression pattern and localization of alpha-synuclein in the human enteric nervous system

Expression pattern and localization of alpha-synuclein in the human enteric nervous system

Background: Alpha-synuclein (α-syn) is abundantly expressed in the central nervous system and involved in the regulation of neurotransmission. Insoluble fibrils of phosphorylated α-synuclein (p-α-syn) have been implicated in several neurodegenerative diseases (e.g. Parkinson's disease, Alzheime...

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Bibliographic Details
Main Authors: Martina Böttner, Dimitri Zorenkov, Ines Hellwig, Martina Barrenschee, Jonas Harde, Tobias Fricke, Günther Deuschl, Jan-Hendrik Egberts, Thomas Becker, Annette Fritscher-Ravens, Alexander Arlt, Thilo Wedel
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neurobiology of Disease
Subjects:
α-synuclein
Enteric nervous system
Neuropathies
Human colon
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002665

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http://www.sciencedirect.com/science/article/pii/S0969996112002665

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