The Transcription Factor HAND1 Is Involved in Cortical Bone Mass through the Regulation of Collagen Expression

The Transcription Factor HAND1 Is Involved in Cortical Bone Mass through the Regulation of Collagen Expression

Temporal and/or spatial alteration of collagen family gene expression results in bone defects. However, how collagen expression controls bone size remains largely unknown. The basic helix-loop-helix transcription factor HAND1 is expressed in developing long bones and is involved in their morphogenes...

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Bibliographic Details
Main Authors: Noriko Funato, Yuki Taga, Lindsay E. Laurie, Chisa Tometsuka, Masashi Kusubata, Kiyoko Ogawa-Goto
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
transcription factors
collagen
microRNAs
cortical bone
periosteum
X-ray microtomography
Online Access:https://www.mdpi.com/1422-0067/21/22/8638

Internet

https://www.mdpi.com/1422-0067/21/22/8638

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