Associations between polygenic risk, negative symptoms, and functional connectome topology during a working memory task in early-onset schizophrenia
Abstract Working memory (WM) deficit in schizophrenia is thought to arise from a widespread neural inefficiency. However, we do not know if this deficit results from the illness-related genetic risk and influence the symptom burden in various domains, especially in patients who have an early onset i...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-06-01
|
Series: | npj Schizophrenia |
Online Access: | https://doi.org/10.1038/s41537-022-00260-w |