Maternal microchimerism is prevalent in cord blood in memory T cells and other cell subsets, and persists post-transplant

Maternal microchimerism is prevalent in cord blood in memory T cells and other cell subsets, and persists post-transplant

Among reported advantages of umbilical cord blood (CB) in transplantation is lower leukemia relapse probability. Underlying cellular mechanisms of graft-vs.-leukemia (GVL) are thought to include a prominent role for T cells. Cells of the CB's mother, maternal microchimerism (MMc), were recently...

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Bibliographic Details
Main Authors: Sami B. Kanaan, Hilary S. Gammill, Whitney E. Harrington, Stephen C. De Rosa, Philip A. Stevenson, Alexandra M. Forsyth, Judy Allen, Emma Cousin, Koen van Besien, Colleen S. Delaney, J. Lee Nelson
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:OncoImmunology
Subjects:
cellular subsets
cord blood
graft-versus-leukemia
hematopoietic transplantation
maternal microchimerism
t cells
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1311436

Internet

http://dx.doi.org/10.1080/2162402X.2017.1311436

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