Gefitinib and methotrexate to resolve tubal ectopic pregnancy: the GEM3 RCT

Gefitinib and methotrexate to resolve tubal ectopic pregnancy: the GEM3 RCT

Background Tubal ectopic pregnancies can cause significant morbidity or even death. Current treatment is with methotrexate or surgery. However, methotrexate treatment can fail in approximately 30% of women. Gefitinib, an epidermal growth factor receptor inhibitor, may improve the effects of methotre...

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Bibliographic Details
Main Authors: Moakes Catherine A, Tong Stephen, Middleton Lee J, Duncan W Colin, Mol Ben W, Whitaker Lucy H R, Jurkovic Davor, Coomarasamy Arri, Nunes Natalie, Holland Tom, Clarke Fiona, Sutherland Lauren C, Doust Ann M, Daniels Jane P, Horne Andrew W
Format: Article
Language:English
Published: NIHR Journals Library 2023-06-01
Series:Efficacy and Mechanism Evaluation
Subjects:
ectopic pregnancy
methotrexate
gefitinib
randomised controlled trial
Online Access:https://doi.org/10.3310/NNZF1037

Internet

https://doi.org/10.3310/NNZF1037

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