MiR-192 directly binds and regulates Dicer1 expression in neuroblastoma.

Neuroblastoma (NB) arises from the embryonic neural crest and is the most common extracranial solid tumor in children under 5 years of age. Reduced expression of Dicer1 has recently been shown to be in correlation with poor prognosis in NB patients. This study aimed to investigate the mechanisms tha...

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Main Authors: Galina Feinberg-Gorenshtein, Avital Guedj, Keren Shichrur, Marta Jeison, Drorit Luria, Yona Kodman, Shifra Ash, Meora Feinmesser, Liat Edry, Noam Shomron, Abraham Weizman, Isaac Yaniv, Smadar Avigad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815303?pdf=render