Influenza a virus host shutoff disables antiviral stress-induced translation arrest.

Influenza a virus host shutoff disables antiviral stress-induced translation arrest.

Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells, generating mRNAs that bear 5' caps and poly(A) tails, and which are exported to the cytoplasm and translated by host machinery. Host antiviral defences include mechanisms that detect the stress of virus infe...

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Bibliographic Details
Main Authors: Denys A Khaperskyy, Mohamed M Emara, Benjamin P Johnston, Paul Anderson, Todd F Hatchette, Craig McCormick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4092144?pdf=render

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http://europepmc.org/articles/PMC4092144?pdf=render

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