The psoriatic shift induced by interleukin 17 is promptly reverted by a specific anti-IL-17A agent in a three-dimensional organotypic model of normal human skin culture

Interleukin 17A (IL-17A), mainly produced by the T helper subclass Th17, plays a key role in the psoriatic plaque formation and progression. The clinical effectiveness of anti-IL-17A agents is documented, but the early and specific mechanisms of their protection are not identified yet. The challenge...

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Bibliographic Details
Main Authors: Elena Donetti, Giulia Lombardo, Serena Indino, Laura Cornaghi, Francesca Arnaboldi, Leonardo Pescitelli, Franz Baruffaldi Preis, Francesca Prignano
Format: Article
Language:English
Published: PAGEPress Publications 2020-04-01
Series:European Journal of Histochemistry
Subjects:
Online Access:https://www.ejh.it/index.php/ejh/article/view/3115