Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T cells.

Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T cells.

Lymphatic filariasis can be associated with development of serious pathology in the form of lymphedema, hydrocele, and elephantiasis in a subset of infected patients.To elucidate the role of CD4(+) T cell subsets in the development of lymphatic pathology, we examined specific sets of cytokines in in...

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Bibliographic Details
Main Authors: Subash Babu, Sajid Q Bhat, N Pavan Kumar, Angelo B Lipira, Sanath Kumar, C Karthik, V Kumaraswami, Thomas B Nutman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2666805?pdf=render

Internet

http://europepmc.org/articles/PMC2666805?pdf=render

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