Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner

Abstract Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens at standard (TS) and thermoneutral (TN) housing tem...

Full description

Bibliographic Details
Main Authors: Maria E. Moreno-Fernandez, Vishakha Sharma, Traci E. Stankiewicz, Jarren R. Oates, Jessica R. Doll, Michelle S. M. A. Damen, Maha A. T. A. Almanan, Claire A. Chougnet, David A. Hildeman, Senad Divanovic
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-021-00157-0