Genetic Labeling of Cells Allows Identification and Tracking of Transgenic Platelets in Mice

Genetic Labeling of Cells Allows Identification and Tracking of Transgenic Platelets in Mice

Background: The use of knock-out mouse models is crucial to understand platelet activation and aggregation. Methods: Analysis of the global double fluorescent Cre reporter mouse <i>mT/mG</i> that has been crossbred with the megakaryocyte/platelet specific <i>PF4-Cre</i> mouse...

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Bibliographic Details
Main Authors: Irena Krüger, Friedrich Reusswig, Kim Jürgen Krott, Celina Fabienne Lersch, Martina Spelleken, Margitta Elvers
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
platelets
megakaryocytes
<i>loxP</i>
Cre recombinase
double fluorescent Cre reporter mouse
<i>PF4-Cre</i>
Online Access:https://www.mdpi.com/1422-0067/22/7/3710

Internet

https://www.mdpi.com/1422-0067/22/7/3710

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