Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice

Abstract Vitronectin (VTN) is a glycoprotein enriched in the blood and activates integrin receptors. VTN blood levels increase only in female mice 24 h after an ischemic stroke and exacerbate brain injury through IL‐6‐driven inflammation, but the VTN induction mechanism is unknown. Here, a 30 min mi...

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Bibliographic Details
Main Authors: Matthew P. Keasey, Chiharu Lovins, Cuihong Jia, Theo Hagg
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15301