Induction of Autophagy Promotes Clearance of RHOP23H Aggregates and Protects From Retinal Degeneration

Induction of Autophagy Promotes Clearance of RHOP23H Aggregates and Protects From Retinal Degeneration

Autophagy is a critical metabolic process that acts as a major self-digestion and recycling pathway contributing to maintain cellular homeostasis. An emerging field of research supports the therapeutic modulation of autophagy for treating human neurodegenerative disorders, in which toxic aggregates...

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Bibliographic Details
Main Authors: Daniela Intartaglia, Giuliana Giamundo, Federica Naso, Edoardo Nusco, Simona Di Giulio, Francesco Giuseppe Salierno, Elena Polishchuk, Ivan Conte
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Ezrin
RHOP23H/+
autophagy
retinal degeneration
ER-stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.878958/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.878958/full

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