Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid.

DNA double-strand breaks (DSBs) are harmful lesions that arise mainly during replication. The choice of the sister chromatid as the preferential repair template is critical for genome integrity, but the mechanisms that guarantee this choice are unknown. Here we identify new genes with a specific rol...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Sandra Muñoz-Galván, Sonia Jimeno, Rodney Rothstein, Andrés Aguilera
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS Genetics
Länkar:http://europepmc.org/articles/PMC3554610?pdf=render