Extracellular vesicles carrying miRNA-181b-5p affects the malignant progression of acute lymphoblastic leukemia

Abstract Objective To investigate how serum extracellular vesicles (EVs)-carried miRNA-181b-5p affected the proliferation, cell cycle and apoptosis of acute lymphoblastic leukemia (ALL) cells. Methods Differentially expressed miRNAs related to ALL were screened by bioinformatics analysis, and the lo...

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Bibliographic Details
Main Authors: Wei Yan, Li Song, Huihan Wang, Wei Yang, Liang Hu, Ying Yang
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-03174-w