Mutation Analysis of Consanguineous Moroccan Patients with Parkinson’s Disease Combining Microarray and Gene Panel

Mutation Analysis of Consanguineous Moroccan Patients with Parkinson’s Disease Combining Microarray and Gene Panel

During the last two decades, 15 different genes have been reported to be responsible for the monogenic form of Parkinson’s disease (PD), representing a worldwide frequency of 5–10%. Among them, 10 genes have been associated with autosomal recessive PD, with PRKN and PINK1 being the most frequent. In...

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Bibliographic Details
Main Authors: Ahmed Bouhouche, Christelle Tesson, Wafaa Regragui, Mounia Rahmani, Valérie Drouet, Houyam Tibar, Zouhayr Souirti, Rafiqua Ben El Haj, Naima Bouslam, Mohamed Yahyaoui, Alexis Brice, Ali Benomar, Suzanne Lesage
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Neurology
Subjects:
Parkinson’s disease
Moroccan patients
consanguinity
chromosomal microarray analysis
next-generation sequencing gene panel
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00567/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00567/full

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