The regulatory function of sphingosine-1-phosphate signaling axis on regulatory T cells in colorectal cancer

In tumors associated with inflammation such as inflammatory bowel disease (IBD) and colorectal cancer (CRC), high numbers of regulatory T cells (Tregs) are associated with both favorable and poor prognoses. The functions of Tregs in CRC remain elusive and have yet to be clearly defined. With new evi...

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Bibliographic Details
Main Authors: Andrew V. Nguyen, Yuan-Yuan Wu, Elaine Y. Lin
Format: Article
Language:English
Published: AIMS Press 2015-02-01
Series:AIMS Molecular Science
Subjects:
Online Access:http://www.aimspress.com/article/10.3934/molsci.2015.1.34/fulltext.html